Unveiling Two New Clinical Trials

We are thrilled to announce the initiation of two groundbreaking clinical trials, marking significant strides in the field of sarcoma research. These trials, Abbisko Pimicotimib and PEAK, hold promise in advancing treatment options for patients facing GIST and TGCT challenges.

Abbisko Pimicotimib Trial: Embarking on a phase III journey, this trial is actively recruiting patients with inoperable TGCT (formerly known as PVNS). The study explores the efficacy of pimicotinib, a novel oral TKI, compared to a placebo, with permitted crossover. This represents a crucial step towards addressing the unique challenges posed by inoperable TGCT.

PEAK Trial: A phase III trial open for enrollment, PEAK focuses on patients with advanced GIST who are progressing or intolerant to imatinib. The trial investigates the combination of sunitinib and bezuclastinib versus sunitinib alone, offering a potential paradigm shift in the management of GIST cases.

We invite all eligible patients to consider participation, and healthcare professionals to reach out for patient enrollment. These trials signify our commitment to advancing sarcoma care, and we look forward to the impactful insights they will undoubtedly yield. Stay tuned for updates as we push the boundaries of sarcoma research.

Two New Promising Treatments

Exciting developments in sarcoma research have brought forth two promising treatments that hold immense potential for transforming the landscape of sarcoma care. SaRC-Q is thrilled to share the latest breakthroughs: Nirogacestat and CART Therapy.

1. Nirogacestat: Opening New Avenues in Sarcoma Treatment
Nirogacestat, a novel investigational drug, has shown promise in inhibiting the Notch signaling pathway, a key player in the growth of certain types of sarcoma. Early clinical trials indicate encouraging results, suggesting that Nirogacestat could be a game-changer in the pursuit of more effective and targeted sarcoma therapies. SaRC-Q is closely monitoring and participating in ongoing research to further evaluate the potential of Nirogacestat in the fight against sarcoma.

2. CART Therapy: Revolutionizing Immunotherapy for Sarcoma
Chimeric Antigen Receptor T-cell (CART) Therapy is an innovative form of immunotherapy that harnesses the power of the patient’s immune system to target and destroy sarcoma cells. This groundbreaking approach involves genetically modifying a patient’s T cells to express receptors that recognize and attack cancer cells. SaRC-Q is actively involved in exploring the efficacy and safety of CART Therapy in sarcoma patients through clinical trials. And, we are happy to share that the first patient was enrolled through McGill to Calgary’s CART Clinical trial. SaRC-Q remains dedicated to staying at the forefront of sarcoma research, relentlessly pursuing advancements that can make a meaningful difference in the lives of patients.

We will continue to provide updates on these promising treatments as we work towards a future where sarcoma is no longer a life-altering threat. Stay tuned for more updates, and let’s journey together towards a brighter future in sarcoma care!

First patient enrolled in new Clinical Trial

Thanks to the efforts and dedication of our co-founder Dr. Ramy Saleh, McGill enrolled the first patient into the Calgary’s Cart T cell trial for advanced alveolar soft-part sarcoma.

SaRC-Q Co-founder Dr. Ramy Saleh Leads Milestone in Sarcoma Research
In a significant milestone for sarcoma research, SaRC-Q co-founder Dr. Ramy Saleh has played a pivotal role in enrolling the first patient into the Calgary’s CART T-cell trial for advanced alveolar soft-part sarcoma (ASPS).

A Step Forward in Advanced Alveolar Soft-Part Sarcoma Treatment
Dr. Ramy Saleh’s dedication and tireless efforts have led to McGill’s enrollment in the cutting-edge CART T-cell trial, offering hope to those facing advanced alveolar soft-part sarcoma. CART T-cell therapy, a revolutionary immunotherapy approach, involves harnessing the patient’s immune system to target and combat cancer cells.

A Testament to SaRC-Q’s Commitment
This achievement underscores SaRC-Q’s commitment to pushing the boundaries of sarcoma research. Dr. Saleh’s leadership exemplifies the collaborative spirit and unwavering dedication of our team in advancing innovative treatments for rare and challenging forms of sarcoma.

A Brighter Future in Sarcoma Care
SaRC-Q congratulates Dr. Ramy Saleh and the entire team at McGill for this groundbreaking accomplishment. Enrolling the first patient into the Calgary’s CART T-cell trial is a significant step forward in our collective mission to transform the future of sarcoma care.

Stay tuned for further updates as we continue to strive for advancements that make a meaningful impact on the lives of sarcoma patients.