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Nirogacestat is a new medication, sold under the brand name OGSIVEO®, that works by blocking a pathway called the Notch signaling pathway in the body. This pathway is important for controlling how cells grow, change, and die. By blocking a specific enzyme called gamma-secretase, Nirogacestat stops this pathway from working properly. This helps to slow down or stop the growth of tumors in the body. It is used to treat Desmoid Tumors.